elearning.med.unideb.hu
Title of the course: Understanding medical problems through experiments
Curse type: required elective course
The teaching Department: Dept. Medical Chemistry
Year and semester: 1st year 2nd semester (course is open to 2nd and 3rd year students as well)
Prerequisite: Medical Chemistry
Entrance conditions: a maximum of 10 (minimum 1) students (preference will be given to students who obtained excellent marks in Medical Chemistry)
Lecturers: staff of the Dept. Medical Chemistry
Cordinator: László Virág /
Credit: 3
The curse’s objective: The course provides a unique opportunity to investigate important medical problems at the cellular and molecular level or in animal experiments. Enrolled students choose a topic from the list below. Students will work in small groups (2-3 students/group) and will be assigned a tutor who will supervise their activities and labwork. First, students make a thorough literature search to understand the medical problem in question, its possible experimental approach and then discuss it in detail with their tutor. During the laboratory sessions, the students perform experiments related to the chosen problem and will learn how to collect data, interpret and evaluate results, how to analyze data statistically and how to draw conclusions. The students prepare assays (5 pages) on their achievements. In a closing session, the group and the tutor discuss the results and evaluate the project.
Scheduling the course is fully flexible and requires prior discussion with supervisor of the chosen topic.
The week-to week program of the course depends on the topics chosen.
Recommended readings: Recommended readings (mostly scientific publications) will depend on the project chosen and will be provided by the tutors.
Exam: Submission of a project summary
Exam type: AW5
Molecular biology techniques and their application
The methods of molecular biology have been used in current clinical diagnosis and gene therapies based on the progress in molecular biology are close to introduction. The goal of our course is to describe basic molecular biology techniques that are used in medical practice in seminars and to demonstrate these methods in practical classes. A set of videotapes will be used to show experimental approaches and the evaluation of results.
Pathobiochemistry of oxidative stress
Signal transfer and protein phosphorylation
Covalent modification of specific intracellular proteins by phosphorylation and dephosphorylation serves a key role in the cellular regulation.This general regulatory mechanism can be found in all cell types affecting various intracellular phenomena. After a short introductory course detailed and up-to-date cover of specialized topics on protein kinases and phosphatases will be given.
Updated: 2017.09.12.
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