Research papers, 2020

Kovács, T., Mikó, E., Ujlaki, Gy., Sári, Zs., Bai, P.: The microbiome as a component of the tumor microenvironment. könyvfejezet: Birbrair, A. (ed.): Tumor Microenvironment, Advances in Experimental Medicine and Biology 1225, Springer Nature Switzerland AG 2020, Chapter 10, 137-153 (2020)


Hegedűs, Cs., Boros, G., Fidrus, E., Kis, G.N., Antal, M., Juhász, T., Janka, E.A., Jankó, L., Parag, Gy., Emri, G., Bai, P., Remenyi, É.: PARP1 inhibition augments UVB-mediated mitochondrial changes – implications for UV-induced DNA repair and photocarcrinogenesis. Cancers 12(5), pp. 1-29 (2020)


Kiss, B., Szántó, M., Hegedűs, Cs., Antal, D., Szödényi, A., Márton, J., Méhes, G., Virág, L., Szegedi, A., Bai, P.: Poly(ADP-ribose) polymerase-1 depletion enhances the severity of inflammation in an imiquimod-induced model of psoriasis. Experimental Dermatoloty 29, 79-85 (2020)


Szántó, M., Bai, P.: The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation and metabolism. Genes and Development 34, 1-20 (2020)


Csernus, B., Bíró, S., Babinszky, L., Komlósi, I., Jávor, A., Stündl, L., Remenyik, J., Bai, P., Oláh, J., Pesti-Asbóth, G., Czeglédi, L.: Effect of carotenoids, oligosaccharides and anthocyanins on growth performance, immunological parameters and intestinal morphology in broiler chickens challenged with Escherichia coli lipopolysaccharide. Animals 10 (347), 1-20 (2020)


Jankó, L., Sári, Zs., Kovács, T., Kis, G., Szántó, M., Antal, M., Juhász, G., Bai, P.: Silencing of PARP2 blocks autophagic degradation. Cells 9 (380), 1-21 (2020)


Docsa, T., Bhattarai, D., Sipos, Á., Wade, C.E., Cox, C.S., Uray, K.: CXCL1 is upregulated during the development of ileus resulting in decreased intestinal contractile activity. Neurogastroenterology and Motility 32, pp. 1-12,  e13757 (2020)


Vida, A., Bodrogi, B.L., Balogh, B., Bai, P.: Taxamat: automated biodiversity data management tool – implications for microbiome studies. Physiology International 107 (1), 12-17 (2020)


Kiss, A., Ráduly, A.P., Regdon, Zs., Polgár, Zs., Tarapcsák, Sz., Sturniolo, I., El-Hamoly, T., Virág, L., Hegedűs, Cs.: Targeting nuclear NAD+ synthesis inhibits DNA repair, impairs metabolic adaptation increases chemosensitivity of U-2OS osteosarcoma cells. Cancers 12,  (1180) 1-21 (2020)


Lontay, B., Kiss, A., Virág, L., Tar, K.: How do post-translational modifications influence the pathomechanistic landscape of Huntington’s disease? A comprehensive review. International Journal of Molecular Sciences 21, 4282, 1-34 (2020)


Szabó, Z., Marosvölgyi, T., Szabó, É., Bai, P., Figler, M., Verzár, Zs.: The potential beneficial effect of EPA and DHA supplementation managing cytokine storm in Coronavirus Disease. Frontiers in Physiology 11, 1-5 (2020)


Alatshan, A., Kovács, G.E., Aladdin, A., Czimmerer, Zs., Tar, K., Benkő, Sz.: All-trans retinoic acid enhances both the signalling for priming and the glycolysis for activation of NLRP3 inflammasome in human macrophage. Cells 9, 1-21 (2020)


Douida, A., Batista, F., Robaszkiewicz, A., Boto, P., Aladdin, A., Szenykiv, M., Czinege, R., Virág, L., Tar, K.: The proteasome activator PA200 regulates expression of genes involved in cell survival upon selective mitochondrial inhibition in neuroblastoma cells.

Journal of Cellular and Molecular Medicine 24, 6716-6730 (2020)


Kiss, B., Mikó, E., Sebő, É., Tóth, J., Ujlaki, Gy., Szabó, J., Uray, K., Bai, P., Árkosy, P.: Oncobiosis and microbial metabolite signaling in pancreatic adenocarcinoma. Cancers 12, 1068, 1-27 (2020) 


Uray, K., Major, E., Lontay, B.: MicroRNA regulatory pathways in the control of the actin-myosin cytoskeleton. Cells 9, 1649, 1-32 (2020)


Sári, Zs., Mikó, E., Kovács, T., Jankó, L., Csonka, T., Lente, G., Sebő, É., Toth, J., Tóth, D., Árkosy, P., Boratkó, A., Ujlaki, Gy., Török, M., Kovács, I., Szabó, J., Kiss, B., Méhes, G., Goedert, J.J., Bai, P.: Indolepropionic acid, a metabolite of the microbiome, has cytostatic properties in breast cancer by activating AHR and PXR receptors and inducing oxidative stress. Cancers 12, 2411, pp. 1-27 (2020)


Nagy, L., Béke, F., Juhász, L., Kovács, T., Juhász-Tóth, É., Docsa, T., Tóth, A., Gergely, P., Somsák, L., Bai, P.: Glycogen phosphorylase inhibitor, 2,3-bis[(2E)-3-(4-hydroxyphenyl)prop-2-enamido] butanedioic acid (BF142), improves baseline insulin secretion of MIN6 insulinoma cells.  Plos One 15(9), pp. 1-15 (2020)


Sári, Zs., Kovács, T., Csonka, T., Török, M., Sebő, É., Toth, J., Tóth, D., Mikó, E., Kiss, B., Szeőcs, D., Uray, K., Karányi, Zs., Kovács, I., Méhes, G., Árkosy, P., Bai, P.: Fecal expression of Escherichia coli lysine decarboxylase (LdcC) is downregulated in E-cadherin negative lobular breast carcinoma. Physiology International 107 (2), 349-358 (2020)


Curtin, N., Bányai, K., Thaventhiran, J., Le Quesne, J., Helyes, Zs., Bai, P.: Repositioning PARP inhibitors for SARS-CoV-2 infecdtion (COVID-19); a new multipronged therapy for acute respiratory distress syndrome? British Journal of Pharmacology 177, 3635-3645 (2020)


Dongaonkar, R.M., Quick, C.M., Laine, G.A., Uray, K., Cox C.S., Stewart, R.H.: Adaptation of the hepatic transudation barrier to sinusoidal hypertension. American Journal of Physiology, Regulatory, Integrative and Comparative Physiology 318(4), R722-R729 (2020)


Uray, K.S., Peng, Z., Cattano, D., Eltzschig, K., Doursout, M-F.: Development of pulmonary fibrosis after heart failure induced by elevated left atrial pressure. American Journal of Translational Research 12 (8), 4639-4647 (2020)


Sári, Zs., Mikó, E., Kovács, T., Boratkó, A., Ujlaki, Gy., Jankó, L., Kiss, B., Uray, K., Bai, P.: Indoxylsulfate, a metabolite of the microbiome, has cytostatic effects in breast cancer via activation of AHR and PXR receptors and induction of oxidative stress. Cancers 12, 2915, pp. 1-23 (2020)


Aladdin, A., Yao, Y., Yang, C., Kahlert, G., Ghani, M., Király, N., Boratkó, A., Uray, K., Dittmar, G., Tar, K.: The proteasome activators Blm10/PA200 enhance the proteasomal degradation of N-terminal Huntingtin. Biomolecules 2020 10, 1581, p: 1-33 (2020)


Smolková, K., Mikó, E., Kovács, T., Leguina-Ruzzi, A., Sipos, A., Bai, P.: Nuclear Factor Erythroid 2-related Factor 2 in regulating cancer metabolism. Antioxidants and Redox Signaling 33 (1), 966-997 (2020)


Curtin, N., Bai, P.: PARPs, PAR and NAD metabolism and their inhibitors in cancer. Cancers 12, 3494, pp. 1-3 (2020)


Csernus, B., Bíró, S., Stündl, L., Remenyik, J., Bai, P., Fehér, M., Minya, D., Czeglédi, L.: Effects of bioactive plant expracts on the immune-related gene expression of common carp (Cyprinus carpio)..Acta Agraria Debreceniensis 2020-2, 49-56 (2020)


Mészáros, B., Papp, F., Mocsár, G., Kókai, E., Kovács, K., Tajti, G., Panyi, Gy.: The voltage-gated proton channel hHv1 is functionally expressed in human chorion-derived mesenchymal stem cells. Scientific Reports 10:7100, pp 1-16 (2020)


Méhes, G., Matolay, O., Beke, L., Czenke, M., Pórszász, R., Mikó, E., Bai, P., Berényi, E., Trencsényi, Gy.: Carbonic anhydrase inhibitor acetazolamide enhances CHOP treatment response and stimulates effector T-cell infiltration in A20/BalbC murine B-cell lymphoma. International Journal of Molecular Sciences 21, 5001, p:1-14 (2020)


Lódi, M., Bánhegyi, V., Bódi, B., Gyöngyösi, A., Kovács, Á., Árokszállási, A., Hamdani, N., Fagyas, M., Édes, I., Csanádi, Z., Czuriga, I., Kisvárday, Z., Lekli, I., Bai, P., Tóth, A., Papp, Z., Czuriga, D.: Prophylactic, single-drug cardioprotection in a comparative, experimental study of doxorubicin-induced cardiomyopathy. Journal of Translational Medicine 18:470, p. 1-18 (2020)


Herrera, J., Bockhorst, K., Bhattarai, D., Uray, K.: Gastrointestinal vascular permeability changes following spinal cord injury. Neurogastroenterology and Motility 2020 (32), p 1-10 (2020)


Goyard, D., Kónya, B., Czifrák, K., Larini, P., Dermontrond, F., Leroy, J., Balzarin, S., Tournier, M., Tousch, D., Petit, P., Duret, C., Maurel, P., Docsa, T., Gergely, P., Somsák, L., Praly, J-P., Azay-Milhau, J., Vidal, S.: Glucose-based spiro-oxathiazoles as in vivo anti-hyperglycemic agents through glycogen phosphorylase inhibition

Organic and Biomolecular Chemistry 18, 931-940 (2020)



Updated: 2021.04.26.

Dear User!


The University of Debrecen considers the protection of personal data and the information provided to be of paramount importance. We hereby inform you that the University of Debrecen has reviewed its processes and incorporated the requirements of GDPR into his own data management and data protection activities, which entered mandatory on may 25,2018. The personal data of the users has been carefully handled by the University of Debrecen, it complies with the applicable data management regulations.Following the requirements of GDPR, we updated our Privacy Statement, which you can access by clicking on the link below: Privacy Policy.

I have read, understand and agree to terms.